Jay D Horton: h-index, Total Citations, and Citation Map

Tip: clickto hide a row from the map

Tap a paper to see who cited it

• SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

  2002·6687 citations

• Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European …

  2017·5170 citations

• Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

  2004·5042 citations

• Molecular mediators of hepatic steatosis and liver injury

  2004·2833 citations

• Human fatty liver disease: old questions and new insights

  2011·2672 citations

• Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European …

  2020·1929 citations

• Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

  2003·1769 citations

• Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

  2004·1037 citations

• Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

  1996·1036 citations

• Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

  1997·1032 citations

• Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases …

  2007·1011 citations

• Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

  1999·1001 citations

• Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

  2002·980 citations

• Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

  1997·973 citations

• A highly durable RNAi therapeutic inhibitor of PCSK9

  2017·961 citations

• Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

  2005·939 citations

• Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus

  1999·928 citations

• Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice

  2006·887 citations

• Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

  1998·876 citations

• Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

  2008·861 citations